Genome-wide association study leads to novel genetic insights into resistance to Aspergillus flavus in maize kernels.

ABSTRACT:

Background

Fungus infection in staple grains affects the food storage and threatens food security. The Aspergillus flavus is known to infect multiple grains and produce mycotoxin Aflatoxin B1, which is mutagenic, teratogenic and causes immunosuppression in animals. However, the molecular mechanism of maize resistance to A. flavus is largely unknown.

Results

Here we used corn kernels to investigate resistance genes to A. flavus using genome-wide association study (GWAS) of 313 inbred lines. We characterized the resistance levels of kernels after inoculating with A. flavus. The GWAS with 558,529 SNPs identified four associated loci involving 29 candidate genes that were linked to seed development, resistance or infection, and involved in signal pathways, seed development, germ

SUBMITTER: Han G 

PROVIDER: S-EPMC7216483 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature