Gut microbiota in early pregnancy among women with Hyperglycaemia vs. Normal blood glucose.

ABSTRACT:

Background

Recent studies suggest that there is a link between the gut microbiota and glucose metabolism. This study aimed to compare the gut microbiota during early pregnancy of women with hyperglycymia to those with normal blood glucose.

Methods

Gut microbial composition was analysed in 22 women with hyperglycaemia and 28 age-matched healthy controls during their first prenatal visits (< 20 weeks) using high throughput sequencing of the V3-V4 region of the 16S ribosomal RNA gene. Hyperglycemia was diagnosed based on the criteria recommended by the International Association of Diabetes and Pregnancy Study Groups in 2010.

Results

Women with hyperglycemia in pregnancy (HIP) had significantly lower microbial richness and diversity compared with healthy pregnant women. T

SUBMITTER: Gao B 

PROVIDER: S-EPMC7216510 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature