The seasonal development dynamics of the yak hair cycle transcriptome.

ABSTRACT:

Background

Mammalian hair play an important role in mammals' ability to adapt to changing climatic environments. The seasonal circulation of yak hair helps them adapt to high altitude but the regulation mechanisms of the proliferation and differentiation of hair follicles (HFs) cells during development are still unknown. Here, using time series data for transcriptome and hormone contents, we systematically analyzed the mechanism regulating the periodic expression of hair development in the yak and reviewed how different combinations of genetic pathways regulate HFs development and cycling.

Results

This study used high-throughput RNA sequencing to provide a detailed description of global gene expression in 15 samples from five developmental time points during the yak hair cyc

SUBMITTER: Bao P 

PROVIDER: S-EPMC7216598 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature