Forensic features and genetic background exploration of a new 47-autosomal InDel panel in five representative Han populations residing in Northern China.

ABSTRACT:

Background

Insertion/deletion (InDel) analysis plays an indispensable role in human identification, population genetics, and biogeographic research. Profiles of individuals in forensic applications worldwide based on a set of autosomal InDel loci (A-InDels) in human genomes have been widely used over the past few years.

Methods

The new AGCU InDel 50 Kit contains 47 well-chosen A-InDels, ensuring high discriminatory power, and the 2 Y chromosome InDel loci (Y-InDels) are used for sex determination in case of allele dropout at Amelogenin. In this study, five Northern Han populations residing in different geographic areas of China were recruited and genotyped using the assay.

Results

After Bonferroni correction, all 47 A-InDels were in accordance with the lack of signifi

SUBMITTER: Song F 

PROVIDER: S-EPMC7216812 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature