Improving PCASL at ultra-high field using a VERSE-guided parallel transmission strategy.

ABSTRACT:

Purpose

To improve the labeling efficiency of pseudo-continuous arterial spin labeling (PCASL) at 7T using parallel transmission (pTx).

Methods

Five healthy subjects were scanned on an 8-channel-transmit 7T human MRI scanner. Time-of-flight (TOF) angiography was acquired to identify regions of interest (ROIs) around the 4 major feeding arteries to the brain, and B1+ and B₀ maps were acquired in the labeling plane for tagging pulse design. Complex weights of the labeling pulses for each of the 8 transmit channels were calculated to produce a homogenous radiofrequency (RF) -shimmed labeling across the ROIs. Variable-Rate Selective Excitation (VERSE) pulses were also implemented as a part of the labeling pulse train. Whole-brain perfusion-weighted images were acquire

SUBMITTER: Tong Y 

PROVIDER: S-EPMC7216913 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature