Treatment and disease-related complications in multiple myeloma: Implications for survivorship.

ABSTRACT: New treatments have transformed multiple myeloma into a chronic disease. Hence, optimal management of treatment and disease-related complications remains a critical component of survivorship care. Survivorship care model in cancers requiring a fixed-duration therapy may not be applicable to myeloma, since patients are exposed to multiple lines of continuous therapy along the disease trajectory. The two most common therapy-related causes of death, which require special consideration, are infection and second cancers. Identifying patients at a high risk of toxicities will facilitate individualized treatment selection and designing clinical trials for protective strategies targeting those patients. For example, prophylactic antibiotic or immunoglobulin replacement can be tested for primary pr

SUBMITTER: Chakraborty R 

PROVIDER: S-EPMC7217756 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature