Endosulfan exposure alters transcription of genes involved in the detoxification and stress responses in Physella acuta.

ABSTRACT: Endosulfan is a persistent pesticide that has been in use for more than five decades. During this time, it has contaminated soil, air, and water reservoirs worldwide. It is extremely toxic and harmful to beneficial non-target invertebrates, aquatic life, and even humans upon consumption, which is one of the many dangers of this pesticide since it biomagnifies in the food chain. The effects of three endosulfan concentrations (1, 10, and 100 µg/L) on the freshwater snail Physella acuta, an invasive cosmopolitan species, were examined over a week-long exposure period. Alterations in the expression of ten genes related to stress and xenobiotic detoxification were measured against the endogenous controls rpL10 and GAPDH by Real-Time polymerase chain reaction. Four genes are described here for t

SUBMITTER: Alonso-Trujillo M 

PROVIDER: S-EPMC7217849 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature