Novel Nomograms Individually Predicting Overall Survival of Non-metastatic Colon Cancer Patients.

ABSTRACT: Background: This study aimed to develop an effective prognostic nomogram for predicting non-metastatic colon cancer. Methods: The Surveillance, Epidemiology, and End Results program was utilized to analyze patients who underwent surgical therapy (25,350 for training, 10,860 for validation). Nomograms were created depending upon multivariate analysis in the training cohort and were compared to current American Joint Committee on Cancer (AJCC) classifications. Areas under the receiver-operating characteristic curves (AUCs), Akaike's information criterions (AICs), and calibration curves were used. The clinical benefit was measured using decision curve analyses (DCAs). The validation cohort was used to validate the results. Results: Nomogram 1 included age, gender, histological grade, T stage,

SUBMITTER: Pei JP 

PROVIDER: S-EPMC7218119 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature