A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

ABSTRACT: SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers-individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease-present a unique opportunity to reveal human genetic determinants of infection and disease.

SUBMITTER: Casanova JL 

PROVIDER: S-EPMC7218368 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature