Promising advances in clinical trials of dental tissue-derived cell-based regenerative medicine.

ABSTRACT:

Background

Advances in regenerative medicine with stem cells have led to clinical trials. Dental/oral tissues are emerging as promising cellular sources of human mesenchymal stem cells. Recently, dental tissue-derived cells have been used clinically due to their great potential, easy accessibility, and ability to be obtained via methods with low invasiveness. The aim of this study is to systematically assess the clinical effectiveness of dental cell-mediated therapies compared to current evidence-based methods in human patients.

Methods

The electronic databases MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and ClinicalTrials.gov were searched up to December 2019 for clinical trials. Clinical trials with any intervention using stem cells/cells derived fro

SUBMITTER: Yamada Y 

PROVIDER: S-EPMC7218566 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature