Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide.

ABSTRACT:

Background

Shifts in data sharing policy have increased researchers' access to individual participant data (IPD) from clinical studies. Simultaneously the number of IPD meta-analyses (IPDMAs) is increasing. However, rates of data retrieval have not improved. Our goal was to describe the challenges of retrieving IPD for an IPDMA and provide practical guidance on obtaining and managing datasets based on a review of the literature and practical examples and observations.

Methods

We systematically searched MEDLINE, Embase, and the Cochrane Library, until January 2019, to identify publications focused on strategies to obtain IPD. In addition, we searched pharmaceutical websites and contacted industry organizations for supplemental information pertaining to recent advances in indu

SUBMITTER: Ventresca M 

PROVIDER: S-EPMC7218569 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature