Multi-omics reveals that the rumen microbiome and its metabolome together with the host metabolome contribute to individualized dairy cow performance.

ABSTRACT:

Background

Recently, we reported that some dairy cows could produce high amounts of milk with high amounts of protein (defined as milk protein yield [MPY]) when a population was raised under the same nutritional and management condition, a potential new trait that can be used to increase high-quality milk production. It is unknown to what extent the rumen microbiome and its metabolites, as well as the host metabolism, contribute to MPY. Here, analysis of rumen metagenomics and metabolomics, together with serum metabolomics was performed to identify potential regulatory mechanisms of MPY at both the rumen microbiome and host levels.

Results

Metagenomics analysis revealed that several Prevotella species were significantly more abundant in the rumen of high-MPY cows, contributi

SUBMITTER: Xue MY 

PROVIDER: S-EPMC7218573 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature