Transgenerational epigenetic effects from male exposure to endocrine-disrupting compounds: a systematic review on research in mammals.

ABSTRACT: Assessing long-term health effects from a potentially harmful environment is challenging. Endocrine-disrupting compounds (EDCs) have become omnipresent in our environment. Individuals may or may not experience clinical health issues from being exposed to the increasing environmental pollution in daily life, but an issue of high concern is that also the non-exposed progeny may encounter consequences of these ancestral exposures. Progress in understanding epigenetic mechanisms opens new perspectives to estimate the risk of man-made EDCs. However, the field of epigenetic toxicology is new and its application in public health or in the understanding of disease etiology is almost non-existent, especially if it concerns future generations. In this review, we investigate the literature on transge

SUBMITTER: Van Cauwenbergh O 

PROVIDER: S-EPMC7218615 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature