Mnemonic strategy training increases neocortical activation in healthy older adults and patients with mild cognitive impairment.

ABSTRACT: Learning and memory deficits characterize the diagnosis of amnestic mild cognitive impairment (aMCI), which is widely viewed as a clinical precursor to Alzheimer's type dementia. There is a growing interest in non-pharmacologic interventions, such as mnemonic strategies, for improving learning and memory in patients with aMCI as well as for maintaining functioning in healthy older adults. Using an ecologically relevant object-location association paradigm, we conducted a randomized, controlled, single-blind study in which healthy older adults and patients with aMCI were randomized to either mnemonic strategy training or a control group that was matched for stimulus exposure. We previously reported that mnemonic strategy training resulted in significantly greater learning and memory improve

SUBMITTER: Hampstead BM 

PROVIDER: S-EPMC7218756 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature