Independent association of tobacco use with opioid use disorder in patients of European ancestry with chronic non-cancer pain.

ABSTRACT:

Background

The harms associated with prescription opioid abuse have become a public health crisis. There is a need for evidence-based objective markers of the risk of opioid use disorder (OUD) in patients with pain receiving opioid treatment. The objective of this study was to evaluate the independent association of tobacco use and OUD in patients with chronic non-cancer pain.

Methods

This cross-sectional naturalistic study evaluated 798 adults ≥ 18 years with chronic non-cancer pain treated with long-term opioid therapy (≥ 6 months) who either developed an OUD (cases, n = 216) or displayed no evidence of an OUD (controls, n = 582). The primary outcome was presence of OUD. In addition to current self-reported tobacco use (primary predictor), covariates included demographics,

SUBMITTER: Cheatle MD 

PROVIDER: S-EPMC7219106 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature