Graduated compression stockings as adjuvant to pharmaco-thromboprophylaxis in elective surgical patients (GAPS study): randomised controlled trial.

ABSTRACT:

Objectives

To investigate whether the use of graduated compression stockings (GCS) offers any adjuvant benefit when pharmaco-thromboprophylaxis is used for venous thromboembolism prophylaxis in patients undergoing elective surgery.

Design

Open, multicentre, randomised, controlled, non-inferiority trial.

Setting

Seven National Health Service tertiary hospitals in the United Kingdom.

Participants

1905 elective surgical inpatients (≥18 years) assessed as being at moderate or high risk of venous thromboembolism were eligible and consented to participate.

Intervention

Participants were randomly assigned (1:1) to receive low molecular weight heparin (LMWH) pharmaco-thromboprophylaxis alone or LMWH pharmaco-thromboprophylaxis and GCS.

Outcome measures

Th

SUBMITTER: Shalhoub J 

PROVIDER: S-EPMC7219517 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature