Colloidal Gels for Guiding Endothelial Cell Organization via Microstructural Morphology.

ABSTRACT: One of the fundamental challenges in vascular morphogenesis is to understand how the microstructural morphology of a 3D matrix can provide the spatial cues to organize the endothelial cells (ECs) into specific vascular structures. Colloidal gels can provide well-controlled distinct morphological matrices because these gels are formed by the aggregation of particles. By altering the aggregation mode, the spatial organization of the particles can be controlled to yield different microstructural morphology. To demonstrate this, colloidal aggregates and gels were developed by electrostatic interaction-mediated aggregation of cationic polyurethane (PU) colloidal particles by using low molecular weight electrolyte and polyelectrolyte to develop microstructurally different colloidal gels without

SUBMITTER: Yuan Y 

PROVIDER: S-EPMC7219539 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature