Effective photoacoustic absorption spectrum for collagen-based tissue imaging.

ABSTRACT:

Significance

Collagen is a basic component of many tissues such as tendons, muscles, and skin, and its imaging helps diagnose and monitor treatments in a variety of fields, including orthopedics. However, due to the overlapping peaks of the absorption spectrum with water in the short-wave infrared region (SWIR), it is difficult to select an optimal wavelength and obtain the photoacoustic (PA) image for collagen-based tissues. Therefore, an additional approach to selecting the proper wavelength is needed.

Aim

The aim of this study is to derive an effective PA absorption spectrum of collagen to select the optimal wavelength for high-sensitive PA imaging (PAI).

Approach

We measure the absorption spectrum by acquiring the PA signal from various collagen-based samples. To

SUBMITTER: Park E 

PROVIDER: S-EPMC7219632 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature