Association of West African ancestry and blood pressure control among African Americans taking antihypertensive medication in the Jackson Heart Study.

ABSTRACT: African Americans have a wide range of continental genetic ancestry. It is unclear whether racial differences in blood pressure (BP) control are related to ancestral background. The authors analyzed data from the Jackson Heart Study, a cohort exclusively comprised of self-identified African Americans, to assess the association between estimated West African ancestry (WAA) and BP control (systolic and diastolic BP < 140/90 mm Hg). Three nested modified Poisson regression models were used to calculate prevalence ratios for BP control associated with the three upper quartiles, separately, vs the lowest quartile of West African ancestry. The authors analyzed data from 1658 participants with hypertension who reported taking all of their antihypertensive medications in the previous 24 hours. WAA

SUBMITTER: Van Tassell JC 

PROVIDER: S-EPMC7219977 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature