Association of 17q24 rs1859962 gene polymorphism with prostate cancer risk: A systematic review and meta-analysis.

ABSTRACT: BACKGROUND:Recently, several genome-wide association studies have demonstrated a cumulative association of 17q24 rs1859962 gene variants with prostate cancer (PCa) risk, but conflicting results on this issue have been reported. Hence, we performed a systematic literature review and meta-analysis to assess the association between 17q24 rs1859962 gene and PCa risk. METHODS:Systematic literature searches were conducted with PubMed, EMBASE, Science Direct/Elsevier, CNKI, and the Cochrane Library up to January 2019 for studies focusing on the association of 17q24 rs1859962 gene polymorphism with PCa risk. Meta-analysis was performed with Review Manager and stata software. Combined OR were identified with 95% confidence intervals (95% CI) in a random or fixed effects model. RESULTS:Eight studies

SUBMITTER: Ren F 

PROVIDER: S-EPMC7220075 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature