CTLA-4 rs5742909 polymorphism and cervical cancer risk: A meta-analysis.

ABSTRACT:

Background

Number of studies have been performed to evaluate the relationship between the cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) gene variant rs5742909 polymorphism and cervical cancer risk, but the sample size was small and the results were conflicting. This meta-analysis was conducted to comprehensively evaluate the overall association.

Methods

PubMed, Web of Science, Embase, China Biology Medical Literature database, China National Knowledge Infrastructure, WanFang, and Weipu databases were searched before July 31, 2018. The strength of associations was assessed using odds ratios (ORs) and 95% confidence intervals (CIs). All of the statistical analyses were conducted using Review Manager 5.3 and Stata 14.0.

Results

Eleven studies involved 3899 cases a

SUBMITTER: Hu S 

PROVIDER: S-EPMC7220313 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature