Positive Fluid Balance and Association with Post-Traumatic Acute Kidney Injury.

ABSTRACT:

Background

Acute kidney injury (AKI) is common in severely injured trauma patients and is associated with poor outcomes. A positive fluid balance is associated with AKI and poor long-term renal outcomes among general ICU and cardiac surgery patients. Currently, the optimal endpoint of resuscitation of severely injured trauma patients is unknown, which may result in excess fluid administration. We hypothesized that positive fluid balance is common after severe trauma and is associated with increased AKI development.

Study design

A cohort study of adult (≥16 years old) trauma patients requiring ICU admission from January 2017 to June of 2017 was conducted. Patients were excluded for early death, rhabdomyolysis, or previous history of end-stage renal disease or congestive heart

SUBMITTER: Hatton GE 

PROVIDER: S-EPMC7220831 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature