Colorectal Cancer Study with Nanostructured Sensors: Tumor Marker Screening of Patient Biopsies.

ABSTRACT: Despite the great progress in screening techniques and medical treatments, colorectal cancer remains one of the most widespread cancers in both sexes, with a high death rate. In this work, the volatile compounds released from human colon cancer tissues were detected by a set of four different chemoresistive sensors, made with a nanostructured powder of metal-oxide materials, inserted into an innovative patented device. The sensor responses to the exhalation of a primary cancer sample and of a healthy sample (both of the same weight, collected during colorectal surgery from the intestine of the same patient) were statistically analyzed. The sensors gave reversible, reproducible, and fast responses for at least one year of continuous use, making them quite superior in respect to the existing

SUBMITTER: Astolfi M 

PROVIDER: S-EPMC7221558 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature