Hydrocortisone and bronchopulmonary dysplasia: variables associated with response in premature infants.

ABSTRACT:

Objective

The primary objective was to evaluate hydrocortisone's efficacy for decreasing respiratory support in premature infants with developing bronchopulmonary dysplasia (BPD). Secondary objectives included assessment of the impact of intrauterine growth restriction (IUGR), maternal history of chorioamnionitis, side effects and route of administration associated with hydrocortisone's efficacy. Dexamethasone as second-line treatment to decrease respiratory support was reviewed.

Methods

Retrospective chart review of preterm infants requiring respiratory support receiving hydrocortisone.

Results

A total of 48 patients were included. Successful extubation was achieved in 50% of intubated patients after hydrocortisone treatment with no major complications. In our small

SUBMITTER: Clauss C 

PROVIDER: S-EPMC7222054 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature