Risk and risk factors for disability pension among patients with treatment resistant depression- a matched cohort study.

ABSTRACT: BACKGROUND:Treatment resistant depression (TRD) is common among patients with depression, and is associated with clinical and functional disability. However, the risk and risk factors for being granted disability pension (DP) among patients with TRD have not been investigated. METHODS:All antidepressant initiators in Sweden with a diagnosis of depression in specialized care were identified in nationwide registers 2006-2013 and followed regarding treatment trials. TRD was defined as the start of a third sequential trial. Patients with TRD who were not on DP (N = 3204) were matched by age, sex, history of depression, calendar year, and time for treatment start with 3204 comparators with depression and ongoing antidepressant treatment. A proportional Cox Regression was performed with DP as ou

SUBMITTER: Taipale H 

PROVIDER: S-EPMC7222563 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature