Oxygen saturation histograms predict nasal continuous positive airway pressure-weaning success in preterm infants.

ABSTRACT:

Background

Continuous positive airway pressure (CPAP) is widely used in preterm infants. Identification of readiness for weaning from CPAP can balance benefits with risks of CPAP exposure. We tested the hypothesis that preterm infants that successfully transition off CPAP have higher oxygen saturations prior to weaning compared with infants who fail weaning from CPAP.

Methods

This was a single-center-matched case-control study in infants ≤30 weeks' gestation receiving ≤30% FiO₂ weaned off CPAP during the first postnatal week. Cases were infants placed back on CPAP within 7 days of being taken off CPAP, whereas control infants remained off CPAP for 7 consecutive days following CPAP discontinuation. Infants were matched on gestational age at birth (±10 days). Prospe

SUBMITTER: Gentle SJ 

PROVIDER: S-EPMC7223394 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature