Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine.

ABSTRACT:

Objective

To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults.

Design

A task force involving 13 international experts and three methodologists used the GRADE approach for guideline development.

Methods

The task force identified four main topics: red blood cell transfusion thresholds, red blood cell transfusion avoidance strategies, platelet transfusion, and plasma transfusion. The panel developed structured guideline questions using population, intervention, comparison, and outcomes (PICO) format.

Results

The task force generated 16 clinical practice recommendations (3 strong recommendations, 13 conditional recommendations), and identified five PICOs with insufficient evidence to mak

SUBMITTER: Vlaar AP 

PROVIDER: S-EPMC7223433 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature