Molecular Characteristics of Burkholderia pseudomallei Collected From Humans in Hainan, China.

ABSTRACT: Melioidosis is a common infectious disease in Southeast Asia and Northern Australia. In Hainan, several cases have been reported, but no systematic study has yet been done on the molecular epidemiology profiles of the organism. An investigation of the molecular epidemiology links and population structure of Burkholderia pseudomallei would help to better understand the clonally of the isolates and differences among them. In this study, multilocus variable-number tandem repeat analysis (MLVA), and multilocus sequence typing (MLST) were applied to examine the epidemiological relatedness and population structure of 166 B. pseudomallei isolates obtained during 2002-2014 in Hainan, China. Both the MLVA_4 and MLST approaches had high discriminatory power for this population, with diversity indice

SUBMITTER: Zhu X 

PROVIDER: S-EPMC7223694 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature