Benefit-to-risk balance of bronchoalveolar lavage in the critically ill. A prospective, multicenter cohort study.

ABSTRACT:

Purpose

To assess the benefit-to-risk balance of bronchoalveolar lavage (BAL) in intensive care unit (ICU) patients.

Methods

In 16 ICUs, we prospectively collected adverse events during or within 24 h after BAL and assessed the BAL input for decision making in consecutive adult patients. The occurrence of a clinical adverse event at least of grade 3, i.e., sufficiently severe to need therapeutic action(s), including modification(s) in respiratory support, defined poor BAL tolerance. The BAL input for decision making was declared satisfactory if it allowed to interrupt or initiate one or several treatments.

Results

We included 483 BAL in 483 patients [age 63 years (interquartile range (IQR) 53-72); female gender: 162 (33.5%); simplified acute physiology score II: 48 (I

SUBMITTER: Kamel T 

PROVIDER: S-EPMC7223716 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature