Do-not-intubate orders in patients with acute respiratory failure: a systematic review and meta-analysis.

ABSTRACT:

Purpose

To assess the rates and variability of do-not-intubate orders in patients with acute respiratory failure.

Methods

We conducted a systematic review of observational studies that enrolled adult patients with acute respiratory failure requiring noninvasive ventilation or high-flow nasal cannula oxygen from inception to 2019.

Results

Twenty-six studies evaluating 10,755 patients were included. The overall pooled rate of do-not-intubate orders was 27%. The pooled rate of do-not-intubate orders in studies from North America was 14% (range 9-22%), from Europe was 28% (range 13-58%), and from Asia was 38% (range 9-83%), p = 0.001. Do-not-intubate rates were higher in studies with higher patient age and in studies where do-not-intubate decisions were made without repor

SUBMITTER: Wilson ME 

PROVIDER: S-EPMC7223954 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature