Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis.

ABSTRACT:

Purpose

Previous studies assessing impact of acute respiratory distress syndrome (ARDS) on mortality have shown conflicting results. We sought to assess the independent association of ARDS with in-hospital mortality among intensive care unit (ICU) patients with sepsis.

Methods

We studied two prospective sepsis cohorts drawn from the Early Assessment of Renal and Lung Injury (EARLI; n = 474) and Validating Acute Lung Injury markers for Diagnosis (VALID; n = 337) cohorts. ARDS was defined by Berlin criteria. We used logistic regression to compare in-hospital mortality in patients with and without ARDS, controlling for baseline severity of illness. We also estimated attributable mortality, adjusted for illness severity by stratification.

Results

ARDS occurred in 195 EARL

SUBMITTER: Auriemma CL 

PROVIDER: S-EPMC7224051 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature