Software Tools for Model-Informed Precision Dosing: How Well Do They Satisfy the Needs?

ABSTRACT: Model-informed precision dosing (MIPD) software tools are used to optimize dosage regimens in individual patients, aiming to achieve drug exposure targets associated with desirable clinical outcomes. Over the last few decades, numerous MIPD software tools have been developed. However, they have still not been widely integrated into clinical practice. This study focuses on identifying the requirements for and evaluating the performance of the currently available MIPD software tools. First, a total of 22 experts in the field of precision dosing completed a web survey to assess the importance (from 0; do not agree at all, to 10; completely agree) of 103 pre-established software tool criteria organized in eight categories: user-friendliness and utilization, user support, computational aspects,

SUBMITTER: Kantasiripitak W 

PROVIDER: S-EPMC7224248 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature