Retention of patients in opioid substitution treatment: A systematic review.

ABSTRACT: BACKGROUND:Retention in opioid substitution (OST) treatment is associated with substantial reductions in all cause and overdose mortality. This systematic review aims to identify both protective factors supporting retention in OST, and risk factors for treatment dropout. METHODS:A systematic search was performed using MEDLINE, Embase, PsycInfo, CINAHL and Web of Science (January 2001 to October 2019). Randomised controlled trials (RCTs) and observational cohort studies reporting on retention rates and factors associated with retention in OST were included. Factors associated with treatment retention and dropout were explored according to the Maudsley Addiction Profile. A narrative synthesis is provided. RESULTS:67 studies were included in this review (4 RCTs and 63 observational cohort stu

SUBMITTER: O'Connor AM 

PROVIDER: S-EPMC7224511 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature