Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19.

ABSTRACT:

Background

Hydroxychloroquine has been widely administered to patients with Covid-19 without robust evidence supporting its use.

Methods

We examined the association between hydroxychloroquine use and intubation or death at a large medical center in New York City. Data were obtained regarding consecutive patients hospitalized with Covid-19, excluding those who were intubated, died, or discharged within 24 hours after presentation to the emergency department (study baseline). The primary end point was a composite of intubation or death in a time-to-event analysis. We compared outcomes in patients who received hydroxychloroquine with those in patients who did not, using a multivariable Cox model with inverse probability weighting according to the propensity score.

Results

SUBMITTER: Geleris J 

PROVIDER: S-EPMC7224609 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature