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Thirty years of CMV seroprevalence-a longitudinal analysis in a German university hospital.


ABSTRACT: Human cytomegalovirus (CMV) is a significant cause of morbidity and mortality in patient groups at risk. We have previously shown that the anti-CMV IgG seroprevalence in an urban region of Germany has changed over the last decades. Overall, a decline from 63.7 to 57.25% had been observed between 1988-1997 and 1998-2008 (p?

SUBMITTER: Hoehl S 

PROVIDER: S-EPMC7225192 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Thirty years of CMV seroprevalence-a longitudinal analysis in a German university hospital.

Hoehl Sebastian S   Berger Annemarie A   Ciesek Sandra S   Rabenau Holger F HF  

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20200127 6


Human cytomegalovirus (CMV) is a significant cause of morbidity and mortality in patient groups at risk. We have previously shown that the anti-CMV IgG seroprevalence in an urban region of Germany has changed over the last decades. Overall, a decline from 63.7 to 57.25% had been observed between 1988-1997 and 1998-2008 (p < 0,001). Here, we continuously follow the trends to the most recent decade 2009 to 2018. In a retrospective analysis, we determined the seroprevalence of CMV IgG antibodies in  ...[more]

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