Local Overheating of Biotissue Labeled With Upconversion Nanoparticles Under Yb³⁺ Resonance Excitation.

ABSTRACT: Local overheating of biotissue is a critical step for biomedical applications, such as photothermal therapy, enhancement of vascular permeability, remote control of drug release, and so on. Overheating of biological tissue when exposed to light is usually realized by utilizing the materials with a high-absorption cross section (gold, silica, carbon nanoparticles, etc.). Here, we demonstrate core/shell NaYF₄:Yb³⁺, Tm³⁺/NaYF₄ upconversion nanoparticles (UCNPs) commonly used for bioimaging as promising near-infrared (NIR) absorbers for local overheating of biotissue. We assume that achievable temperature of tissue labeled with nanoparticles is high enough because of Yb³⁺ resonance absorption of NIR radiation, whereas the use of auxiliary

SUBMITTER: Krylov IV 

PROVIDER: S-EPMC7225365 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature