Trajectories of Cognitive Function Prior to Cancer Diagnosis: A Population-Based Study.

ABSTRACT:

Background

An emerging body of research suggests that noncentral nervous system cancer may negatively impact the brain apart from effects of cancer treatment. However, studies assessing cognitive function in newly diagnosed cancer patients cannot exclude selection bias and psychological effects of cancer diagnosis. To overcome these limitations, we investigated trajectories of cognitive function of patients before cancer diagnosis.

Methods

Between 1989 and 2013, a total of 2059 participants from the population-based Rotterdam Study were diagnosed with noncentral nervous system cancer. Cognitive assessments were performed every 3 to 5 years using a neuropsychological battery. The general cognitive factor was composed of individual cognitive tests to assess global cognition. U

SUBMITTER: van der Willik KD 

PROVIDER: S-EPMC7225679 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature