Interactions between the MicroRNAs and Microbiota in Cancer Development: Roles and Therapeutic Opportunities.

ABSTRACT: The human microbiota is made up of the fungi, bacteria, protozoa and viruses cohabiting within the human body. An altered microbiota can provoke diseases such as cancer. The mechanisms by which a modified microbiota can intervene in the onset and progression of neoplastic diseases are manifold. For instance, these include the effects on the immune system and the onset of obesity. A different mechanism seems to be constituted by the continuous and bidirectional relationships existing between microbiota and miRNAs. MiRNAs emerged as a novel group of small endogenous non-coding RNAs from that control gene expression. Several works seem to confirm the presence of a close connection between microbiota and miRNAs. Although the main literature data concern the correlations between microbiota, miR

SUBMITTER: Allegra A 

PROVIDER: S-EPMC7225936 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature