Characterization of stimulus response curves obtained with transcranial magnetic stimulation from bilateral tibialis anterior muscles post stroke.

ABSTRACT:

Background

Stimulus response curves (SR curves), measured using transcranial magnetic stimulation (TMS) induced motor evoked potentials (MEP), yield important information regarding corticomotor connectivity. Limited understanding of SR curve analyses techniques for leg muscles after stroke may limit the utility of TMS data for walking recovery.

Objective

To compare linear and non-linear curve fitting for MEP responses from the non-paretic and paretic tibialis anterior (TA) muscles.

Methods

Accuracy of fit was measured using coefficient of determination (R²). Similarities of the fit were compared using slopes and area under the curve (AUC).

Results

The non-linear function demonstrated higher R² and slopes. The AUC was not significantly diff

SUBMITTER: Iyer PC 

PROVIDER: S-EPMC7226675 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature