Ultrasound in managing extrapulmonary tuberculosis: a randomized controlled two-center study.

ABSTRACT:

Background

Patients with clinically suspected tuberculosis are often treated empirically, as diagnosis - especially of extrapulmonary tuberculosis - remains challenging. This leads to an overtreatment of tuberculosis and to underdiagnosis of possible differential diagnoses.

Methods

This open-label, parallel-group, superiority randomized controlled trial is done in a rural and an urban center in Tanzania. HIV-positive and -negative adults (≥18 years) with clinically suspected extrapulmonary tuberculosis are randomized in a 1:1 ratio to an intervention- or control group, stratified by center and HIV status. The intervention consists of a management algorithm including extended focused assessment of sonography for HIV and tuberculosis (eFASH) in combination with chest X-ray and

SUBMITTER: Ndege R 

PROVIDER: S-EPMC7226714 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature