Improving long term patient outcomes from deep brain stimulation for treatment-refractory obsessive-compulsive disorder.

ABSTRACT: Introduction: Deep brain stimulation (DBS) has emerged as an effective treatment for patients with severe treatment-refractory obsessive-compulsive disorder (OCD). Over the past two decades, several clinical trials with multiple years of follow-up have shown that DBS offers long-term symptom relief for individuals with severe OCD, though a portion of patients do not achieve an adequate response.Areas covered: This review sought to summarize the literature on the efficacy and long-term effectiveness of DBS for OCD, and to identify strategies that have the potential to improve treatment outcomes.Expert opinion: Although this literature is just emerging, a small number of DBS enhancement strategies have shown promising initial results. More posterior targets along the str

SUBMITTER: Guzick A 

PROVIDER: S-EPMC7227118 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature