An integrated software for virus community sequencing data analysis.

ABSTRACT:

Background

A virus community is the spectrum of viral strains populating an infected host, which plays a key role in pathogenesis and therapy response in viral infectious diseases. However automatic and dedicated pipeline for interpreting virus community sequencing data has not been developed yet.

Results

We developed Quasispecies Analysis Package (QAP), an integrated software platform to address the problems associated with making biological interpretations from massive viral population sequencing data. QAP provides quantitative insight into virus ecology by first introducing the definition "virus OTU" and supports a wide range of viral community analyses and results visualizations. Various forms of QAP were developed in consideration of broader users, including a command l

SUBMITTER: Wang M 

PROVIDER: S-EPMC7227348 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature