Cerebral Metabolic Changes During Visuomotor Adaptation Assessed Using Quantitative fMRI.

ABSTRACT: The brain retains a lifelong ability to adapt through learning and in response to injury or disease-related damage, a process known as functional neuroplasticity. The neural energetics underlying functional brain plasticity have not been thoroughly investigated experimentally in the healthy human brain. A better understanding of the blood flow and metabolic changes that accompany motor skill acquisition, and which facilitate plasticity, is needed before subsequent translation to treatment interventions for recovery of function in disease. The aim of the current study was to characterize cerebral blood flow (CBF) and oxygen consumption (relative CMRO₂) responses, using calibrated fMRI conducted in 20 healthy participants, during performance of a serial reaction time task which in

SUBMITTER: Foster C 

PROVIDER: S-EPMC7227432 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature