Environmental exposure to metal mixtures and linear growth in healthy Ugandan children.

ABSTRACT:

Background

Stunting is an indicator of poor linear growth in children and is an important public health problem in many countries. Both nutritional deficits and toxic exposures can contribute to lower height-for-age Z-score (HAZ) and stunting (HAZ < -2).

Objectives

In a community-based cross-sectional sample of 97 healthy children ages 6-59 months in Kampala, Uganda, we examined whether exposure to Pb, As, Cd, Se, or Zn were associated with HAZ individually or as a mixture.

Methods

Blood samples were analyzed for a mixture of metals, which represent both toxins and essential nutrients. The association between HAZ and metal exposure was tested using multivariable linear regression and Weighted Quantile Sum (WQS) regression, which uses mixtures of correlated exposures a

SUBMITTER: Moody EC 

PROVIDER: S-EPMC7228047 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature