Arterial stiffness cut-off value and white matter integrity in the elderly.

ABSTRACT:

Objective

Central artery stiffness is a confirmed predictor of cardiovascular health status that has been consistently associated with cognitive dysfunction and dementia. The European Society of Hypertension has established a threshold of arterial stiffness above which a cardiovascular event is likely to occur. However, the threshold at which arterial stiffness alters brain integrity has never been established.

Methods

The aim of this study is to determine the arterial stiffness cut-off value at which there is an impact on the white matter microstructure. This study has been conducted with 53 cognitively elderly without dementia. The integrity of the white matter was assessed using diffusion tensor metrics. Central artery stiffness was evaluated by measuring the carotid-femo

SUBMITTER: Badji A 

PROVIDER: S-EPMC7229323 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature