Health-related quality of life and patient-reported outcome measures in NASH-related cirrhosis.

ABSTRACT:

Background & aims

Non-alcoholic steatohepatitis (NASH) is known to have a negative impact on patients' health-related quality of life (HRQoL), even before progression to cirrhosis has occurred. The burden of NASH-related cirrhosis from the patient perspective remains poorly understood. Herein, we aimed to identify the burden of disease and HRQoL impairment among patients with NASH-related compensated cirrhosis.

Methods

This targeted literature review sought first to identify the humanistic burden of disease from the perspective of patients with diagnosed NASH-cirrhosis and, secondly, to identify generic or disease-specific patient-reported outcome measures (PROMs) used to assess the impact of NASH-cirrhosis. Searches were conducted in bibliographical databases, grey or unpub

SUBMITTER: McSweeney L 

PROVIDER: S-EPMC7229498 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature