Salivary Biomarkers and Their Correlation with Pain and Stress in Patients with Burning Mouth Syndrome.

ABSTRACT: To evaluate a panel of salivary analytes involving biomarkers of inflammation, stress, immune system and antioxidant status in patients with burning mouth syndrome (BMS) and to study their relationship with clinical variables. A total of 51 patients with BMS and 31 controls were consecutively enrolled in the study, with the recording of oral habits, the severity of pain using a visual analogue scale (VAS), the Hospital Anxiety and Depression (HAD) score and the Oral Health Impact Profile-14 (OHIP14) score. Resting whole saliva was collected with the drainage technique, followed by the measurement of 11 biomarkers. The salivary flow was higher in patients with BMS. Among all the biomarkers studied, significantly higher levels of alpha-amylase, immunoglobulin A (IgA), and macrophage inflamma

SUBMITTER: Lopez-Jornet P 

PROVIDER: S-EPMC7230786 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature