MRI study of paraspinal muscles in patients with Amyotrophic Lateral Sclerosis (ALS).

ABSTRACT: the study of paraspinal muscles is pivotal for the diagnosis and staging of Amyotrophic Lateral Sclerosis (ALS), and is usually performed by electromyography. to evaluate the role of paraspinal muscle MRI as a diagnostic biomarker in ALS. we evaluated T1-w images of newly diagnosed ALS patients (n = 14), age-matched healthy controls (n = 11), patients affected by inflammatory myopathy (n = 10), and lumbar radiculopathy (n = 19), and compared them semiquantitatively by using the Mercuri Scale. a significant difference in the appearance of the psoas muscle was observed between ALS patients and patients with radiculopathy (p = 0.003); after stratifying ALS patients into spinal and bulbar onsets, we found a significant difference in the appearance of the longissimus dorsi muscle between the sp

SUBMITTER: Diamanti L 

PROVIDER: S-EPMC7230865 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature