Controllable pH Manipulations in Micro/Nanofluidic Device Using Nanoscale Electrokinetics.

ABSTRACT: Recently introduced nanoscale electrokinetic phenomenon called ion concentration polarization (ICP) has been suffered from serious pH changes to the sample fluid. A number of studies have focused on the origin of pH changes and strategies for regulating it. Instead of avoiding pH changes, in this work, we tried to demonstrate new ways to utilize this inevitable pH change. First, one can obtain a well-defined pH gradient in proton-received microchannel by applying a fixed electric current through a proton exchange membrane. Furthermore, one can tune the pH gradient on demand by adjusting the proton mass transportation (i.e., adjusting electric current). Secondly, we demonstrated that the occurrence of ICP can be examined by sensing a surrounding pH of electrolyte solution. When pH > thresho

SUBMITTER: Park JS 

PROVIDER: S-EPMC7231315 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature