Parietal P3 and midfrontal theta prospectively predict the development of adolescent alcohol use.

ABSTRACT:

Background

Subclinical adolescent alcohol use is highly prevalent and may have deleterious effects on important psychosocial and brain outcomes. Prior research has focused on identifying endophenotypes of pathological drinking, and the predictors of normative drinking remain understudied. This study investigated the incremental predictive value of two potential psychophysiological endophenotypes, P3 amplitude (an index of decision making) and midfrontal theta power (a correlate of attentional control), for prospectively predicting the expression and initiation of alcohol use emerging in adolescence.

Methods

A large (N = 594) epidemiological sample was prospectively assessed at ages 11/14/17. Alcohol/substance use was assessed at all ages via a computerized self-report invent

SUBMITTER: Harper J 

PROVIDER: S-EPMC7231637 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature